Research Article by PNAS About Globally Used Pesticide Atrazine and the Effects On Frogs Intersexuality
Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis) Tyrone B. Hayes tyrone@berkeley.edu, Vicky Khoury, Anne Narayan, +7, and Sherrie GallipeauAuthors Info & Affiliations Edited* by David B. Wake, University of California, Berkeley, CA, and approved January 15, 2010 (received for review August 20, 2009) March 9, 2010 107 (10) 4612-4617 https://doi.org/10.1073/pnas.0909519107 Article online at www.pnas.org [Online] at https://www.pnas.org/doi/full/10.1073/pnas.0909519107 "Abstract The herbicide atrazine is one of the most commonly applied pesticides in the world . As a result, atrazine is the most commonly detected pesticide contaminant of ground, surface, and drinking water. Atrazine is also a potent endocrine disruptor that is active at low, ecologically relevant concentrations . Previous studies showed that atrazine adversely affects amphibian larval development. The present study demonstrates the reproductive conseq